Biopharma Expansion in Delaware: WuXi AppTec says its new Middletown, Delaware drug-manufacturing site will start oral solid dosage work in Q4 2026, with sterile and injectable production following in Q4 2027, as the CRDMO boosts global capex by at least 17% to meet rising demand for peptides and oligonucleotides. Energy Policy Watch: The Trump administration’s next Alaska oil-and-gas lease sale for the Arctic National Wildlife Refuge hits a fresh test Friday, with conservation groups warning of financial and reputational risks and supporters pitching potential jobs and new U.S. oil output. Private Markets Stress: Reuters reports Partners Group is flagging higher withdrawal requests and may cap a second fund, while Blackstone already capped withdrawals at a flagship private credit pool—signaling broader strain across open-ended private credit and private equity. Delaware Courts & IP: A Delaware federal judge trimmed two patents from Harbour Medical’s case against an Amgen unit ahead of trial, calling key mouse-antibody claims “nonsensical,” while other Delaware patent fights continue to narrow. Local Business & Construction: D.R. Horton and Forestar urge Delaware Chancery Court to toss a lot-deal shareholder suit, and PennDOT plans a major bridge replacement on U.S. 1 over Darby Creek in Delaware County, starting this fall. Air Quality Alert: Delaware is under a Code Orange ozone action day Friday, with DNREC urging sensitive groups to limit outdoor activity.